Lecirelin
(Dalmarelin) M.W. 1210
pGlu-His-Trp-Ser-Tyr-D-tertLeu-Leu-Arg-Pro-NHEt
Special
price: $6200 for 2
grams of the peptide, including
delivery.
1. Lecirelin (6-(3-methyl-d-valine)-9-(N-ethyl-L-prolynamide)-10-deglycinamide)
luteinizing
hormone releasing factor, is a synthetic hypothalamic gonadotropin
releasing hormone (GnRH)
analogue. Lecirelin is a nonapeptide, while the natural compound
is a decapeptide; moreover the
glycine aminoacid in the 6th position has been substituted by
leucine.
2. The drug is intended for the induction of ovulation
in cows, mares and rabbits, both for
treatment of such conditions as ovarian cysts and for improvement
of conception rates. The
recommended dosing regime is a single or repeated twice intramuscular
treatment with 50-100 μg
(cow, mare) or 0.5-0.8 μg (rabbit) of active compound...
[Excerpt from the European Agency for the Evaluation of Medicinal
Products, Veterinary Medicines Evaluation Unit summary
report]
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